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1

Syntheses and Biological Properties of Chiral Fluoroalkyl Quinuclidinyl Benzilates

Kiesewetter, Dale O., Silverton, James V., Eckelman, William C.

Journal:

Journal of Medicinal Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 1.07 MB

english, 1995

2

Genomic Evidence Establishes Anatolia as the Source of the European Neolithic Gene Pool

Omrak, Ayça, Günther, Torsten, Valdiosera, Cristina, Svensson, Emma M., Malmström, Helena, Kiesewetter, Henrike, Aylward, William, Storå, Jan, Jakobsson, Mattias, Götherström, Anders

Journal:

Current Biology

Année:

2015

Langue:

english

Fichier:

PDF, 2.31 MB

english, 2015

3

In vivo muscarinic binding of 3-(alkylthio)-3-thiadiazolyl tetrahydropyridines

Dale O. Kiesewetter, Richard E. Carson, Elaine M. Jagoda, Peter Herscovitch, William C. Eckelman

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 258 KB

english, 1999

4

ChemInform Abstract: Synthesis and Evaluation of an 18F Analogue of Forskolin for Imaging Adenylyl Cyclase.

Dale O. Kiesewetter, Mark B. Sassaman, Joan Robbins, Elaine M. Jagoda, Richard E. Carson, Nathan M. Appel, Elizabeth Sutkowski, Peter Herscovitch, Allen Braun, William C. Eckelman

Journal:

Année:

2000

Fichier:

PDF, 36 KB

2000

5

Use of 1,8-bis-(dimethylamino)-naphthalene/H18F complex as new radiofluorinating agent

Giancarlo Pascali, Dale O. Kiesewetter, Piero A. Salvadori, William C. Eckelman

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2004

Langue:

english

Fichier:

PDF, 142 KB

english, 2004

6

Utility of azetidinium methanesulfonates for radiosynthesis of 3-[18F]fluoropropyl amines

Dale O. Kiesewetter, William C. Eckelman

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2004

Langue:

english

Fichier:

PDF, 154 KB

english, 2004

7

Purification of the precursor for the automated radiosynthesis of [18F]FCWAY by counter-current chromatography

Ying Ma, Lixin Lang, Dale O Kiesewetter, Bik-Kee Vuong, Michael Channing, Yoichiro Ito, William C Eckelman

Journal:

Journal of Chromatography A

Année:

2004

Langue:

english

Fichier:

PDF, 243 KB

english, 2004

8

Syntheses and D2 receptor affinities of derivatives of spiperone containing aliphatic halogens

Dale O. Kiesewetter, William C. Eckelman, Robert M. Cohen, Ronald D. Finn, Steven M. Larson

Journal:

International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes

Année:

1986

Langue:

english

Fichier:

PDF, 849 KB

english, 1986

9

Automated synthesis of 18F analogue of paclitaxel (PAC): [18F]Paclitaxel (FPAC)

Joseph D. Kalen, Jerry I. Hirsch, Karen A. Kurdziel, William C. Eckelman, Dale O. Kiesewetter

Journal:

Applied Radiation and Isotopes

Année:

2007

Langue:

english

Fichier:

PDF, 335 KB

english, 2007

10

Synthesis and evaluation of an 18F analog of forskolin for imaging adenylyl cyclase

Dale O Kiesewetter, Mark B Sassaman, Joan Robbins, Elaine M Jagoda, Richard E Carson, Nathan M Appel, Elizabeth Sutkowski, Peter Herscovitch, Allen Braun, William C Eckelman

Journal:

Journal of Fluorine Chemistry

Année:

2000

Langue:

english

Fichier:

PDF, 623 KB

english, 2000

11

Identification of metabolites of fluorine-18-labeled M2 muscarinic receptor agonist, 3-(3-[(3-fluoropropyl)thio]-1,2,5-thiadiazol-4-yl)-1,2,5,6-tetrahydro-1-methylpyridine, produced by human and rat hepatocytes

Ying Ma, Dale O Kiesewetter, Elaine M Jagoda, Bill X Huang, William C Eckelman

Journal:

Journal of Chromatography B

Année:

2002

Langue:

english

Fichier:

PDF, 186 KB

english, 2002

12

Liquid chromatography–tandem mass spectrometry identification of metabolites of three phenylcarboxyl derivatives of the 5-HT1A antagonist, N-(2-(4-(2-methoxyphenyl)-1-piperazinyl)ethyl)-N-(2-pyridyl) trans-4-fluorocyclohexanecarboxamide (FCWAY), produced by human and rat hepatocytes

Ying Ma, Lixin Lang, Dale O Kiesewetter, William C Eckelman

Journal:

Journal of Chromatography B

Année:

2002

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2002

13

In vivo muscarinic 2 receptor imaging in cognitively normal young and older volunteers

Teresa A. Podruchny, Catherine Connolly, Arun Bokde, Peter Herscovitch, William C. Eckelman, Dale O. Kiesewetter, Trey Sunderland, Richard E. Carson, Robert M. Cohen

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 211 KB

english, 2003

14

Higher in vivo muscarinic-2 receptor distribution volumes in aging subjects with an apolipoprotein E-ϵ4 allele

Robert M. Cohen, Teresa A. Podruchny, Arun L.W. Bokde, Richard E. Carson, Peter Herscovitch, Dale O. Kiesewetter, William C. Eckelman, Trey Sunderland

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 86 KB

english, 2003

15

Inhibition of [18F]FP-TZTP binding by loading doses of muscarinic agonists P-TZTP or FP-TZTP in vivo is not due to agonist-induced reduction in cerebral blood flow

Kazuaki Shimoji, Takanori Esaki, Yoshiaki Itoh, Laura Ravasi, Michelle Cook, Jane Jehle, Elaine M. Jagoda, Dale O. Kiesewetter, Kathleen Schmidt, Louis Sokoloff, William C. Eckelman

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 371 KB

english, 2003

16

[76Br]BMK-152, a nonpeptide analogue, with high affinity and low nonspecific binding for the corticotropin-releasing factor type 1 receptor

Elaine M. Jagoda, Lixin Lang, Karen Mccullough, Carlo Contoreggi, B. Moon Kim, Ying Ma, Kenner C. Rice, Lawrence P. Szajek, William C. Eckelman, Dale O. Kiesewetter

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 477 KB

english, 2011

17

Invited Commentary

William B. Kiesewetter

Journal:

World Journal of Surgery

Année:

1980

Langue:

english

Fichier:

PDF, 245 KB

english, 1980

18

Liquid chromatography–tandem mass spectrometry identification of metabolites of two 5-HT1A antagonists, N-{2-[4-(2-methoxylphenyl)piperazino]ethyl}-N-(2-pyridyl) trans- and cis-4-fluorocyclohexanecarboxamide, produced by human and rat hepatocytes

Ying Ma, Lixin Lang, Dale O. Kiesewetter, Elaine Jagoda, Mark B. Sassaman, Margaret Der, William C. Eckelman

Journal:

Journal of Chromatography B: Biomedical Sciences and Applications

Année:

2001

Langue:

english

Fichier:

PDF, 279 KB

english, 2001

19

In vivo muscarinic binding selectivity of (R,S)- and (R,R)-[18F]-Fluoromethyl QNB

Dale O. Kiesewetter, Richard E. Carson, Elaine M. Jagoda, Christopher J. Endres, Margaret G. Der, Peter Herscovitch, William C. Eckelman

Journal:

Bioorganic & Medicinal Chemistry

Année:

1997

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1997

20

Muscarinic Cholinergic Receptor Measurements With [18F]FP-TZTP: Control and Competition Studies

Carson, Richard E., Kiesewetter, Dale O., Jagoda, Elaine, Der, Margaret G., Herscovitch, Peter, Eckelman, William C.

Journal:

Journal of Cerebral Blood Flow and Metabolism

Année:

1998

Langue:

english

Fichier:

PDF, 1.52 MB

english, 1998

21

Metabolites of three phenylcarboxyl derivatives of the 5-HT1A antagonists, way 100635, produced by human and rat hepatocytes

Ying Ma, Lixin Lang, Dale O. Kiesewetter, Mark B. Sassaman, William C. Eckelman

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2001

Langue:

english

Fichier:

PDF, 137 KB

english, 2001

22

Radiochemical synthesis of [18F]fluoropaclitaxel ([18F]FPAC)

Dale O. Kiesewetter, William C. Eckelman

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2001

Langue:

english

Fichier:

PDF, 187 KB

english, 2001

23

Synthesis of 4-[18F]fluorobenzoyllisinopril: A radioligand for angiotensin converting enzyme (ACE) imaging with positron emission tomography

Yu-Hua C. Lee, Dale O. Kiesewetter, Lixin Lang, Elaine M. Jagoda, Jamshid Shirani, Vasken Dilsizian, William C. Eckelman

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Année:

2001

Langue:

english

Fichier:

PDF, 159 KB

english, 2001

24

Defecation and continence

Alois F. Scharli, William B. Kiesewetter

Journal:

Diseases of the Colon & Rectum

Année:

1970

Langue:

english

Fichier:

PDF, 1.59 MB

english, 1970

25

Evaluation of stereoisomers of 4-fluoroalkyl analogues of 3-quinuclidinyl benzilate in in vivo competition studies for the M1, M2, and M3 muscarinic receptor subtypes in brain

Jaetae Lee, Chang H. Paik, Dale O. Kiesewetter, Seok G. Park, William C. Eckelman

Journal:

Nuclear Medicine and Biology

Année:

1995

Langue:

english

Fichier:

PDF, 920 KB

english, 1995

26

Application of LC-MS to the analysis of new radiopharmaceuticals

Ying Ma, Dale Kiesewetter, Lixin Lang, William C Eckelman

Journal:

Molecular Imaging and Biology

Année:

2003

Langue:

english

Fichier:

PDF, 137 KB

english, 2003

27

Species differences in metabolites of PET ligands: serotonergic 5-HT1A receptor antagonists 3-trans-FCWAY and 3-cis-FCWAY

Ying Ma, Lixin Lang, Dale Kiesewetter, Elaine Jagoda, William C. Eckelman

Journal:

Nuclear Medicine and Biology

Année:

2006

Langue:

english

Fichier:

PDF, 489 KB

english, 2006

28

Evaluation of [18F]fluoroxanomeline {5-{4-[(6-[18F]fluorohexyl)oxy]-1,2,5-thiadiazol-3-yl}-1-methyl-1,2,3,6-tetrahydropyridine} in muscarinic knockout mice

Dale O. Kiesewetter, Elaine M. Jagoda, Kazuaki Shimoji, Ying Ma, William C. Eckelman

Journal:

Nuclear Medicine and Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.08 MB

english, 2007

29

An automated one-step one-pot [18F]FCWAY synthesis: development and minimization of chemical impurities

Bik-Kee Vuong, Dale O. Kiesewetter, Lixin Lang, Ying Ma, William C. Eckelman, Michael A. Channing

Journal:

Nuclear Medicine and Biology

Année:

2007

Langue:

english

Fichier:

PDF, 234 KB

english, 2007

30

Imaging of the muscarinic acetylcholine neuroreceptor in rats with the M2 selective agonist [18F]FP-TZTP

Laura Ravasi, Joji Tokugawa, Toshiyuki Nakayama, Jurgen Seidel, Louis Sokoloff, William C. Eckelman, Dale O. Kiesewetter

Journal:

Nuclear Medicine and Biology

Année:

2012

Langue:

english

Fichier:

PDF, 683 KB

english, 2012

31

Striatal adenosine A2A receptor-mediated positron emission tomographic imaging in 6-hydroxydopamine-lesioned rats using [18F]-MRS5425

Abesh Kumar Bhattacharjee, Lixin Lang, Orit Jacobson, Bidhan Shinkre, Ying Ma, Gang Niu, William C. Trenkle, Kenneth A. Jacobson, Xiaoyuan Chen, Dale O. Kiesewetter

Journal:

Nuclear Medicine and Biology

Année:

2011

Langue:

english

Fichier:

PDF, 561 KB

english, 2011

32

Using single photon emission tomography (SPECT) and positron emission tomography (PET) to trace the distribution of muscarinic acetylcholine receptor (MACHR) binding radioligands

Dale O. Kiesewetter, Richard E. Carson, Elaine M. Jagoda, Peter Herscovitch, William C. Eckelman

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 718 KB

english, 1999

33

Fluoro-, bromo-, and iodopaclitaxel derivatives: synthesis and biological evaluation

Dale O Kiesewetter, Elaine M Jagoda, Chih-Hao K Kao, Ying Ma, Laura Ravasi, Kazuaki Shimoji, Lawrence P Szajek, William C Eckelman

Journal:

Nuclear Medicine and Biology

Année:

2003

Langue:

english

Fichier:

PDF, 173 KB

english, 2003

34

Radiochemical synthesis and biodistribution of a novel maxi-K potassium channel opener

Dale O Kiesewetter, Elaine M Jagoda, John E Starrett Jr, Valentin K Gribkoff, Piyasena Hewawasam, Nugahally Srinivas, Daniel Salazar, William C Eckelman

Journal:

Nuclear Medicine and Biology

Année:

2002

Langue:

english

Fichier:

PDF, 153 KB

english, 2002

35

Determination of [18F]FCWAY, [18F]FP-TZTP, and their metabolites in plasma using rapid and efficient liquid-liquid and solid phase extractions

Ying Ma, Dale O Kiesewetter, Lixin Lang, Margaret Der, Bill Huang, Richard E Carson, William C Eckelman

Journal:

Nuclear Medicine and Biology

Année:

2003

Langue:

english

Fichier:

PDF, 169 KB

english, 2003

36

Routine quality control of recycled target [18O]water by capillary electrophoresis and gas chromatography

Bill X. Huang, Michael A. Channing, Paul S. Plascjak, Dale O. Kiesewetter, Margaret Der, Ying Ma, William C. Eckelman

Journal:

Nuclear Medicine and Biology

Année:

2003

Langue:

english

Fichier:

PDF, 77 KB

english, 2003

37

Biologically stable [18F]-labeled benzylfluoride derivatives

Yasuhiro Magata, Lixin Lang, Dale O Kiesewetter, Elaine M Jagoda, Michael A Channing, William C Eckelman

Journal:

Nuclear Medicine and Biology

Année:

2000

Langue:

english

Fichier:

PDF, 360 KB

english, 2000

38

Development of 5-HT1A receptor radioligands to determine receptor density and changes in endogenous 5-HT

Elaine M. Jagoda, Lixin Lang, Joji Tokugawa, Ashlie Simmons, Ying Ma, Carlo Contoreggi, Dale Kiesewetter, William C. Eckelman

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 177 KB

english, 2006

39

Hyperchloremic acidosis as a complication of imperforate anus with recto-urinary fistula

Richard Shepard, William B. Kiesewetter

Journal:

Journal of Pediatric Surgery

Année:

1966

Langue:

english

Fichier:

PDF, 629 KB

english, 1966

40

Hypertrophic pyloric stenosis at the children's hospital of pittsburgh from 1912 to 1967 A critical review of current problems and complications

Alois Schärli, William K. Sieber, William B. Kiesewetter

Journal:

Journal of Pediatric Surgery

Année:

1969

Langue:

english

Fichier:

PDF, 545 KB

english, 1969

41

Imperforate anus: Anorectosigmoid pressure studies as a quantitative evaluation of postoperative continence

Alois F. Scharli, William B. Kiesewetter

Journal:

Journal of Pediatric Surgery

Année:

1969

Langue:

english

Fichier:

PDF, 1.28 MB

english, 1969

42

Anorectal anomalies: A suggested international classification

Thomas V. Santulli, William B. Kiesewetter, Alexander H. Bili Jr.

Journal:

Journal of Pediatric Surgery

Année:

1970

Langue:

english

Fichier:

PDF, 494 KB

english, 1970

43

Rhabdomyosarcoma in infants and children: Factors affecting long-term survival

Frank E. Ehrlich, Joel E. Haas, William B. Kiesewetter

Journal:

Journal of Pediatric Surgery

Année:

1971

Langue:

english

Fichier:

PDF, 524 KB

english, 1971

44

The response of colonic muscle to drugs: An in vitro study of Hirschsprung's disease

Yasuhiko Hiramoto, William B. Kiesewetter

Journal:

Journal of Pediatric Surgery

Année:

1974

Langue:

english

Fichier:

PDF, 564 KB

english, 1974

45

Colo-colic intussusception due to a hemangioma

Richard J. Bower, William B. Kiesewetter

Journal:

Journal of Pediatric Surgery

Année:

1977

Langue:

english

Fichier:

PDF, 879 KB

english, 1977

46

Wilms' tumor: Factors influencing long-term survival

Kamthorn Sukarochana, William B. Kiesewetter

Journal:

The Journal of Pediatrics

Année:

1966

Langue:

english

Fichier:

PDF, 380 KB

english, 1966

47

Hernias—Inguinal and umbilical

William B. Kiesewetter

Journal:

The American Journal of Surgery

Année:

1961

Langue:

english

Fichier:

PDF, 3.29 MB

english, 1961

48

Intestinal obstruction in infancy and childhood

Kare Ohma, William B. Kiesewetter

Journal:

The American Journal of Surgery

Année:

1962

Langue:

english

Fichier:

PDF, 877 KB

english, 1962

49

Imperforate anus: Review of a sixteen year experience with 146 patients

William B. Kiesewetter, C. Randolph Turner, William K. Sieber

Journal:

The American Journal of Surgery

Année:

1964

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1964

50

Imperforate anus: I. Its surgical anatomy

William B. Kiesewetter, H.H. Nixon

Journal:

Journal of Pediatric Surgery

Année:

1967

Langue:

english

Fichier:

PDF, 778 KB

english, 1967